Folding bikes are getting better and there is still a long way to go in finding the best folding system.
Low maintenance is important for a lot of people, so better fully enclosed gears, chains and brakes are important to get normal people cycling, likewise with puncture-resistant tires.
It must be possible to come up with better locking/tracking systems. There have been lots of advances in practical light systems over the last few years, this will continue.
However all the above must be cheap enough that they come as standard on a “cheap” bike brought from the local supermarket; otherwise they don’t have any effect in the “real world”.
I see the biggest need for innovations being aimed at people who see a bike as a transport solution, rather then an object to worship. However most innovations are created by and for people that love bikes.
(My wife can own and drive a car, while knowing nothing about how a car works; she just has to book it into the garage once a year when they send her a reminder [or a "error" light comes on]. How can bike be made as easy to use and own?)