The modern range of Shimano shifters (e.g. FD4700 and related: https://si.shimano.com/pdfs/dm/DM-FD0002-05-ENG.pdf) have a top position for big-small, and a top-trim position for big-big. The difference in derailleur position is tiny from what I can tell, maybe 1mm on my shifters. Would there have been any drawback in performance/setup if they'd made this difference larger, which would mean it was easier to set up the extremes without rub, especially if the frame flexes.
FWIW, the difference between low and low-trim is much larger, maybe 5mm, and it's much more usable because of it.