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I've heard that when you get new wheels you should put a couple hundred miles on them to let everything get set in and get an initial stretch, then do a tune up.
Can I just go by feel and tighten the spokes that seem a litte lose? I don't think the wheels are untrue, they're heavy duty wheels. Are there any tricks to this initial tune up?
As has been mentioned in the comments, you should take it to a shop. You're likely to do more harm than good if you're not already experienced in at least truing and preferably building wheels.
It also might not even take a couple hundred miles. I'd probably check on it once a week or even every couple days. Feel the spokes. Once it gets to a point where there are notable differences in tension, go ahead and take it in.
Don't cut corners or your new wheels won't last as long as they could, or worse, they might not last at all.
There are entire books written on truing bicycle wheels. Before you attempt to maintain your wheels yourself, without the shop, read those books, buy a good truing stand, and even then, practice on wheels you don't care about. There is an art to it.
