I have around 1 year touring experience in South America. Mostly remote dirt roads and trails.
I would never ever purposely run tubes again.
As long as you are confident in your tubeless setup flats should be almost nonexistent. I only carry one tube for emergency that has never been used. A small bottle of spare sealant is pretty essential to top off if you start to get small air leaks. Needle and thread to sew small cuts, as well as tire plugs. A few patches if you are forced to use a tube.
All decently large size cities in Chile and Argentina should be fairly well supplied with bike parts (somewhat less so in other countries in my experience). If not, then it is usually easy to travel by bus somewhere bigger. If you are in big cities (especially capital cities) can be good to stock up or change parts, especially if you are headed to remote areas.
Tubeless sealant is becoming more and more ubiquitous, especially in MTB communities. Usually these guys are not running tubeless specific tires, and they make it work. 650b mountain bike tires will be easier to find than road or gravel tires (could be an issue, not sure what tire clearance a kona rove has?).
SRAM parts can be much trickier to find than Shimano. Old shimano standards are king. Dub and GXP bottom brackets/chainrings could be difficult (especially 1x). I believe Peru only recently has an official SRAM importer.
I would carry plenty of extra brake pads, they are light and depending on your brake model could be difficult to find.
Generally just keep an eye on parts. Be religious about cleaning and oiling your chain. Have a good idea for what is wearing and when you might need to replace it, and plan ahead.