Some shifter designs have become known for causing broken cables, anecedotally because they're causing too much repeat spooling and unspooling over too tight a radius. For example, broken cable heads inside some STI generations is a well-known occurrence.
Other shifters have more cable movement but don't have those issues, a common example being the 1:1 shifters where replacement is done by lifting the cover off the shifter.
How do you design a shifter and stay on the right side of this?