I was intrigued by one of the points mentioned in this question regarding grease fills, namely:
[...] which means that the ball bearings get to distribute the load over the entire surface area, whereas the axle hubs and the cones get the stress in just one continuous band of limited area.
The premise of this statement makes sense to me. In a wheel hub, the bearing cones/inner races are fixed to the axle, which is in turn fixed to the frame/fork. The bearing balls therefore would only contact the lower half of the cone as the bearing's internal clearance means that its upper half is unloaded, as seen in the following diagram:
It is obvious that the cups/outer races rotate with the hub shell and therefore have fairly evenly distributed wear, so they are irrelevant to the question.
Imagine a brand-new wheel (and therefore a hub) that is installed in a frame/fork and then not removed for some period of riding, let's say a year of hard riding. In that time, only that specific section of the cone would be worn. Would it make sense to then intentionally install the wheel in a different orientation at some point in time to allow a different section of the cone to be worn instead?
Taking the situation to an extreme, imagine a wheel that is installed and then never removed again until it is time for bearing replacement. Would the rider be able to extract a bit more life from the bearings by installing the wheel so the axle is rotated 180° from its old position to utilize the unworn side of the cone?
The question could also extend to other bicycle bearings, such as bottom brackets, where the cups/outer races only see wear at the bottom. Could one extract the bearings and then reinstall them upside down to extend their lifespan? Pedal bearings will also see uneven wear due to the rider's foot placement choice.