Have a Grizl with the DT Swiss G1800 wheels. Want to run burlier tyres like the Continental's Race Kings (2.0) and have the original G-Bites (45mm) in reserve for some bikepacking. Both to be run tubeless. Can the tubeless tyre switching (swapping a TL tyre with the intent of someday putting it on again) be considered a detrimental practice? Will the tyre the second or third time it is mounted on a wheel be less performant or could one expect problems mounting it?
I have no practical experience with your question. While I’d defer to someone who does, here’s my reasoning. In theory, it is possible that repeated installations might cause wear, especially to the softer of the materials involved. For example, square taper cranks or BB spindles may wear, especially if installed loosely. However, with good materials and barring installation error, we know that you often have to remove and reinstall square taper cranks many, many times to cause wear.
Keep in mind that it's generally expected that many people may replace a tube once or more during a tire's life. If the beads experienced wear from a couple of installations, I would expect manufacturers to have received complaints and to have addressed that issue by now. I have no idea how many times would cause the beads to stretch or to wear, but I expect that if bead wear exists, it would only show after many installations - a few dozen, at least.
I don’t expect aluminum or carbon rims to wear at all from repeated tire installations. Again, I would defer to someone with actual practical experience or lab test results, but it seems extremely unlikely that the rims would wear.