As a child I was very active, and in a weight-lifting injury I damaged my Coccyx, making it very difficult to sit in the same position for long periods of time. As such, bicycling, what once was a staple joy in my life, has become painful. Is there a seat or frame design that takes pressure off the tail bone so that I can ride pain-free once again?
A good seat should put most of the pressure sitz bones rather than the tail bone. You'll probably want to look for something like the Rido Saddle which has the back cut out and would probably minimize pressure on your coccyx. I can't say whether this type of saddle would work well for you, but in my mind it seems like it might do a good job.
you could check some of the Specialized Body Geometry saddles.
They also feature the back cut out design as recommended by Kibbee, hopefully that should take some pressure off the tail bone.
Also as they come in 3 different widths, you can choose the size that fits you best. The recommended width is determined based on the distance between the sit bones and the ridding position.