I would like to extend my heartfelt thanks to the experts on this forum for their valuable suggestions regarding my nausea during high-altitude cycling climbs. After some research, I discovered the solution to my specific problem and wanted to share my experience here. Please note that these are my personal experiences and solutions and should not be considered medical advice. My age is 44 years!
To find a solution, I studied numerous articles and watched videos on how high-altitude climbers manage their ascents. I focused particularly on Mount Everest climbers and their safety protocols. I discovered that there are two primary factors likely causing my nausea:
- Ascending too quickly (due to the speed of the bicycle)
- Dehydration from extreme exertion and losing moisture through
breathing in the thin, low-oxygen atmosphere.
To address dehydration, I started using electrolyte powder, which also helped with muscular fatigue. Additionally, I made more frequent stops for water intake to stay hydrated.
Acclimatizing to a low-oxygen environment posed a unique challenge. Ascending slowly is critical for adjusting to low oxygen levels at high altitudes, but on a bicycle, slow isn't always an option. Further research led me to the medication "Acetazolamide," commonly used by climbers to accelerate acclimatization. Additionally, a doctor recommended "Ondansetron" to counter nausea. After testing both medications on high-altitude climbs, I found that taking Acetazolamide (125 mg) in the morning and Ondansetron (8 mg) during the final sections, combined with constant electrolyte intake, effectively prevented altitude sickness.
Testing the solution
After these discoveries, I performed some high-altitude climbs to test the effect of these medications. During all these climbs, I ate dates to maintain my nutrition levels. I don’t have many food choices available because I have been a patient of Ulcerative Colitis for the past 11 years.
The first climb involved an elevation gain of 1,925 meters over 33.10 km. The climb started at an altitude of 1,200 meters and reached a maximum altitude of 2,700 meters. The final 6 km section was above 2,500 meters. Usually, I always get nauseous on this track, but this time, I felt no nausea. I took Acetazolamide in the morning of the climb and Ondansetron during the final section.
In the second climb, I traveled 102.88 km with a total elevation gain of 2,263 meters. The final 10 km of the climb were above 2,000 meters, with a maximum altitude of 2,450 meters. I started at 1,200 meters at the beginning of the climb. I wanted to understand whether it was Acetazolamide controlling my nausea or the anti-nausea medication Ondansetron. So, I didn't take Acetazolamide before the climb, and as I reached 1,800 meters, I felt nauseous. I took Ondansetron, but despite that and taking electrolytes throughout the climb, I vomited upon reaching 2,000 meters. My condition improved after I began to descend.
The third climb involved an elevation gain of 1,613 meters over 29.52 km, with the last 6 km above 2,500 meters. The starting altitude was 1,200 meters. This time, I took Acetazolamide in the morning and didn't take Ondansetron until we reached the destination and took some rest. At that moment, I felt a little nauseous, so I took an 8 mg Ondansetron, and my nausea disappeared within 20 minutes.
After these trials and testing my body, I was ready for the final big climb that I had been preparing for over the last six months. Using a similar protocol, I took Acetazolamide in the morning. It was a climb of 19.65 km with an elevation gain of 2,023 meters. The altitude at the start of the climb was 1,700 meters. The last 8 km were above 3,000 meters. I kept myself hydrated and used electrolytes when I felt muscular fatigue, which then disappeared. At 3,500 meters, I felt a bit nauseous, so I took an 8 mg Ondansetron, and my symptoms improved.
After all these trials, I hope I have resolved my issue of feeling nauseous during high-altitude climbs with the combination of three items, acetazolamide, ondansetron, and electrolytes. My all the climbing activities are recorded on my Strava profile as well as on my YouTube channel.